This arrangement of atoms leads, from 121 million people worldwide, a disease characterized by “loss of interest and pleasure, feelings of guilt, loss of self-esteem, disturbed sleep, a drop in form and concentration. ” Thus the World Health Organization describes depression.

Researchers at the Ecole Polytechnique de Lausanne in Switzerland, became interested in a protein located in the hippocampus, the MIF to macrophage migration inhibitory factor. According to their research published in the journal Molecular Psychiatry, inhibition of this protein causes “an increase in anxiety and depressive states.

Contrary to what is often said and written, the neurons are renewed in part, notably in the hippocampus. It speaks of neurogenesis. Previous research had shown that there was a link between neurogenesis and depression. Scientists from the Lausanne show “for the first time” that MIF was present in quantity in the stem cells of the hippocampus and there was a link between this protein and neurogenesis.

To prove it, researchers have inflicted a series of tests in rats genetically or chemically modified not to produce MIF protein. In rodent studies, the absence of this protein induced a slowdown in production of new neurons and thus an increase in anxiety and depressive behavior. [How do you recognize a rat depressed? The issue will be a future article on this blog ... To keep things simple, rapid and succinct, rodents respond differently to stressful situations.]

Indeed, these studies have shown that these mutant rats responded less well to anti-depressants, in this case of fluoxetine, better known under the name of Prozac. In the absence of MIF protein, the molecules of fluoxetine more difficult to relaunch the process of creating new neurons.

Far from being only theoretical, these results could provide, ultimately, profits on the treatment of depression, as noted by the researchers concluded in their report:

“This finding indicates that MIF is potentially significant for the treatment of deficits in the genesis of neurons, as well as problems related to anxiety, depression or cognition.

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Apple, who does not know? The fruit is very popular in the community. Not just popular, this fruit is also recognized many health experts have health benefits for the body. Therefore, in the UK is known proverb: An apple a day keeps the doctor away or eat an apple every day and the body will be spared from the disease.
Here are some benefits of apples:

Lowering cholestero levels
Apples contain phytochemicals known, effective antioxidants against bad cholesterol, in addition to lowering bad cholesterol, apples also increases good cholesterol (HDL). Pectin and acid content of D-glucaric acid in apples contributed to help lower bad cholesterol in the body.

Preventing lung cancer and healthy lung
Flavonid substances in apples may reduce the risk of proven lung cancer lung to 50%. Research from Cornell University in the United States also found that substances in the skin of apple phytochemicals inhibit the growth of colon cancer by 43%.

Preventing heart disease and stroke
Apple proved to prevent stroke. Publication of research in Finland (1996) shows, the pattern of flavonoid-rich food incidence of heart disease is lower.

Lose weight.
As a good source of fiber, apple good for digestion and help you lose weight. Apples are an excellent snack for people who are trying to lose weight because the high fiber content, thus preventing hunger comes more quickly.

Dental hygiene.
Apples also contain tannins, a useful substance to prevent periodontal tooth decay. Gum disease is caused by bacteria stick to each other forming plaque.

Make women stay beautiful
Content of boron in apple shown to help women maintain hormonal levels of estrogen at menopause. Maintaining estrogen means to reduce the distortion caused by hormone imbalance at times menopause, such as hot blast, pain, depression, heart disease, osteoporosis.

Protect the body from the flu virus
Apple cider is very good for attacks against viral infections because of increased immune thanks to the apple juice consumption.

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